Beitragstitel | Potential role of FDG-PET in preoperative assessment of primary salivary gland malignancies |
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Beitragscode | P16 |
Autor:innen | |
Präsentationsform | Poster |
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Abstract-Text |
Purpose: The added value of 18F-fluorodesoxyglucose (FDG positron emission tomography (FDG-PET) head and neck cancer is increasingly recognized. However, its potential role in salivary gland cancer has not been described yet. Methods: A consecutive cohort of 45 salivary gland cancer patients with pretherapeutic FDG-PET that underwent surgical resection was reviewed. Statistical analysis was performed to assess whether pre-treatment metabolic tumor parameters (maximum standardized uptake value – SUVmax) correlated with tumor phenotype. Results: Tumor showing high grade histology had a higher SUVmax (Kruskal Wallis Test P=0.011), that is that SUVmax was higher in salivary duct carcinoma, squamous cell carcinoma and rather low in adenoid cystic and acinic cell carcinoma. Patients with pN+ disease had a significantly higher SUVmax of the primary tumor than patients with pN0 disease (Kruskal Wallis Test, p=0.012). Conclusion: SUVmax of primary tumor may assist in clinical decision-making regarding salivary gland cancer, as a high SUVmax is associated with high-grade histology and positive nodal disease. Clinicians may consider more aggressive surgery for these patients. |