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Beitragstitel Potential role of FDG-PET in preoperative assessment of primary salivary gland malignancies
Beitragscode P16
Autor:innen
  1. Sevda Karimian ORL Klinik Zürich, USZ Präsentierende:r
  2. Martina Broglie-Däppen University Hospital Zurich
  3. Niels Rupp Univeristät Zürich, Unispital Zürich
  4. Martin Hüllner UniversitätsSpital & Universität Zürich
  5. Sandra Nicole Freiberger UniversitätsSpital & Universität Zürich
  6. Grégoire Morand UniversitätsSpital & Universität Zürich
Präsentationsform Poster
Themengebiete
  • Innovation und Zukunftsentwicklung in der ORL
Abstract-Text Purpose: The added value of 18F-fluorodesoxyglucose (FDG positron emission tomography (FDG-PET) head and neck cancer is increasingly recognized. However, its potential role in salivary gland cancer has not been described yet.

Methods: A consecutive cohort of 45 salivary gland cancer patients with pretherapeutic FDG-PET that underwent surgical resection was reviewed. Statistical analysis was performed to assess whether pre-treatment metabolic tumor parameters (maximum standardized uptake value – SUVmax) correlated with tumor phenotype.

Results: Tumor showing high grade histology had a higher SUVmax (Kruskal Wallis Test P=0.011), that is that SUVmax was higher in salivary duct carcinoma, squamous cell carcinoma and rather low in adenoid cystic and acinic cell carcinoma. Patients with pN+ disease had a significantly higher SUVmax of the primary tumor than patients with pN0 disease (Kruskal Wallis Test, p=0.012).

Conclusion: SUVmax of primary tumor may assist in clinical decision-making regarding salivary gland cancer, as a high SUVmax is associated with high-grade histology and positive nodal disease. Clinicians may consider more aggressive surgery for these patients.